Relationships of nucleotide, amino acid sequence and secondary structure of protein and molecular design.
- Author:
Peng MA
1
;
Lian-Jie WANG
Author Information
1. Life College of Science and Engineering, Shaanxi University of Science & Technology, Xianyang, 712081, China. mapeng_true@yahoo.com.cn
- Publication Type:Journal Article
- MeSH:
Amino Acid Sequence;
Amino Acids;
chemistry;
classification;
Cluster Analysis;
Nucleotides;
chemistry;
genetics;
Protein Structure, Secondary;
genetics;
Sequence Analysis, Protein;
methods
- From:
Chinese Journal of Biotechnology
2007;23(6):1082-1085
- CountryChina
- Language:Chinese
-
Abstract:
May the structure information of protein be obtained from the corresponding nucleotide sequence? For this question, a computer program was used to conduct a statistical analysis about the clustering phenomena of amino acids. In this method, 20 kinds of amino acid were classified into 2 types according to the number of hydrogen bonds formed by middle base of their correlation codons. It can be seen that amino acid has a rather great possibility of neighboring on another of its class and this assembly has a tendency to forming specific secondary structure. A sequence was designed and its secondary structure was predicted by this prediction software.
