On-chip magnetic separation of microcantilever immunosensor based on the CdSe QDs-tagged magnetic microbead.
- Author:
Peng GAO
1
;
Suying YAO
;
Bingbo ZHANG
;
Ermao LI
;
Jin CHANG
Author Information
1. School of Electronic and Information Engineering, Tianjin University, Tianjin 300072, China. gp_ysy@163.com
- Publication Type:Journal Article
- MeSH:
Antibodies;
analysis;
Biosensing Techniques;
instrumentation;
methods;
Cadmium Compounds;
chemistry;
Equipment Design;
Immunoassay;
instrumentation;
methods;
Magnetics;
Micro-Electrical-Mechanical Systems;
instrumentation;
Microspheres;
Nanotechnology;
Polystyrenes;
chemistry;
Quantum Dots;
Selenium Compounds;
chemistry
- From:
Chinese Journal of Biotechnology
2008;24(2):315-322
- CountryChina
- Language:Chinese
-
Abstract:
We designed a novel microcantilever immuosensor based on magnetic microbead, applying different-sized CdSe QDs as fluorescent probes and polystyrene magnetic microbead. The novel microcantilever immuosensor used fluorescent probes embedded polystyrene microbeads and specific antibodies on the surface of the polystyrene microbead. In addition, we studied the mechanism of the on-chip magnetic separation, the structure of micro-electromagnet and the microbead magnetization by the micro-magnetic field, the snake-shaped planar micro-electromagnet for the novel microcantilever immuosensor.
