MicroRNAs and prostate cancer.
- Author:
Wen-ting XU
;
Ying-jie JIA
;
Xiao-jiang LI
;
Jun CHEN
- Publication Type:Journal Article
- MeSH:
Disease Progression;
Humans;
Male;
MicroRNAs;
metabolism;
Prognosis;
Prostatic Neoplasms;
chemistry;
genetics;
metabolism;
Receptors, Androgen;
metabolism
- From:
National Journal of Andrology
2015;21(5):458-462
- CountryChina
- Language:Chinese
-
Abstract:
Prostate cancer (PCa) is one of the most common malignancies in the urinary system of males. A growing number of studies have shown that microRNAs, as small ribonucleic acid molecules and a class of non-coding small RNAs, are closely related with PCa and a variety of microRNAs are abnormally expressed in it. This article focuses on the roles of microRNAs in the occurrence and progression of PCa, with a description of differentially expressed microRNAs in PCa and an analysis of their association with its prognosis as well as their correlation with chemotherapy, androgen receptors, and metastasis of PCa.
