Shugan Jieyu Capsules combined with conventional therapy for type III B prostatitis complicated by sexual dysfunction.
- Author:
Wei-hong LANG
;
Hai-bo XIA
- Publication Type:Journal Article
- MeSH: Adrenergic alpha-1 Receptor Antagonists; therapeutic use; Adrenergic alpha-Antagonists; Anxiety; drug therapy; Biofeedback, Psychology; Capsules; Depression; diagnosis; drug therapy; Drugs, Chinese Herbal; therapeutic use; Electric Stimulation Therapy; Humans; Male; Premature Ejaculation; drug therapy; etiology; Prostatitis; complications; drug therapy; Sulfonamides; therapeutic use
- From: National Journal of Andrology 2015;21(6):545-548
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the clinical effect of Shugan Jieyu Capsules (SJC) on type III B prostatitis complicated by sexual dysfunction.
METHODSA total of 98 patients with type III B prostatitis complicated by sexual dysfunction were equally randomized to a control and a trial group, the former treated with the combination of biofeedback/electrical stimulation and the α-blocker Tamsulosin Hydrochloride, and the latter with oral SJC in addition, both for 8 weeks. Before and after treatment, the severity of the symptoms was determined with NIH-CPSI, the patients'sexual function evaluated with CIPE-5 and IIEF-5, and their anxiety, depression and other psychological problems assessed with Hamilton Anxiety Scale (HAMA) and Hamilton Depression Rating Scale ( HAMD). The results were subjected to statistical analysis and compared between the two groups.
RESULTSStatistically significant differences were found between the control and trial groups in the NIH-CPSI score (26.31 ± 7.91 vs 18.84 ± 6.63, P < 0.01), CIPE-5 premature ejaculation score (10. 41 ± 3.03 vs 14.37 ± 2.35, P < 0.05), IIEF-5 score (10.29 ± 3.97 vs 14.69 ± 4.19, P < 0.05), HAMA score (24.31 ± 1.78 vs 13.41 ± 4.21, P < 0.01), and HAMD score (25.24 ± 2.83 vs 14.49 ± 4.44, P < 0.01).
CONCLUSIONSJC can effectively relieve anxiety, depression and other psychological problems in type III B prostatitis patients with sexual dysfunction and improve their clinical symptoms as well.