Shugan Yiyang Capsules for the treatment of asthenospermia: A clinical study.
- Author:
Ya-lei SHI
;
Min-jian ZHANG
;
Wan-jun CHENG
;
Yang-fan OU
- Publication Type:Journal Article
- MeSH: Asthenozoospermia; drug therapy; enzymology; Biomedical Research; Capsules; Carnitine; administration & dosage; therapeutic use; Drug Therapy, Combination; Drugs, Chinese Herbal; therapeutic use; Humans; Male; Semen; enzymology; Spermatozoa; alpha-Glucosidases; analysis
- From: National Journal of Andrology 2015;21(7):634-636
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the clinical efficacy of Shugan Yiyang Capsules in the treatment of asthenospermia and its action mechanisms.
METHODSWe randomly assigned 135 asthenospermia patients to groups A (n = 47), B (n = 45), and C (n = 43) to be treated with Shugan Yiyang Capsules, oral levocarnitine, or combination of the two. We observed sperm quality and the level of α-glucosidase in the seminal plasma before and after medication.
RESULTSThe total effectiveness rate was 70.21% in group A (markedly effective in 16 cases and effective in 17), 68.89% in group B (markedly effective in 15 cases and effective in 16), and 83.72% in group C (markedly effective in 16 cases and effective in 20), significantly higher in C than in A and B (P < 0.05). Both sperm quality and the level of α-glucosidase in the seminal plasma were improved in the three groups of patients, most obviously in group C.
CONCLUSIONShugan Yiyang Capsules can be used for the treatment of asthenospermia, and its effect can be enhanced in combination with oral levocarnitine.