Radical prostatectomy and radiation therapy for high-risk prostate cancer: An update.
- Author:
Jun-hao LEI
;
Yong-ji CHEN
;
Liang-ren LIU
;
Qiang WEI
- Publication Type:Journal Article
- MeSH:
Humans;
Male;
Neoplasm Grading;
Neoplasm Recurrence, Local;
Prostate-Specific Antigen;
blood;
Prostatectomy;
methods;
Prostatic Neoplasms;
blood;
pathology;
radiotherapy;
surgery;
Risk
- From:
National Journal of Andrology
2015;21(7):663-666
- CountryChina
- Language:Chinese
-
Abstract:
Recently, the D'Amico classification system is widely used for the risk stratification of prostate cancer (PCa) , although no consensus has been reached for the definition of high-risk PCa. This system defines high-risk PCa as a prostate-specific antigen (PSA) level > 20 ng/ml, a Gleason score of 8-10, or a clinical stage ≥ T2c. Because high-risk PCa is prone to recurrence and metastasis after treatment, a proper initial therapy plays a crucial role. Currently, radical prostatectomy and radiation therapy are considered to be two most important options for the initial treatment of high-risk PCa although it remains controversial which is better.
