Epithelial mesenchymal transition in prostate cancer: Advances in current research.
- Author:
Bin YAN
;
Ning JIANG
;
Yuan-jie NIU
- Publication Type:Journal Article
- MeSH:
Biomedical Research;
Cell Differentiation;
Disease Progression;
Epithelial Cells;
physiology;
Epithelial-Mesenchymal Transition;
physiology;
Humans;
Male;
Mesenchymal Stromal Cells;
Neoplastic Stem Cells;
physiology;
Prostatic Neoplasms;
pathology
- From:
National Journal of Andrology
2015;21(9):847-851
- CountryChina
- Language:Chinese
-
Abstract:
Epithelial mesenchymal transition (EMT) is a process of normal cell physiological development, in which epithelial cells transform into mesenchyme cells through a specific program. EMT plays a key role in inflammatory reaction, cell development, tumor invasion, and metastasis and has an interrelation with prostate cancer stem cells. Recent researches show the involvement of EMT in the development and metastasis of prostate cancer. This article reviews the specific roles and action mechanisms of EMT in the progression of prostate cancer.
