Recombinant tissue plasminogen activator (r-TPA) in fibrin dissolution due to postoperative endophthalmitis.
- Author:
Yasmin RIAZ
1
;
Jodhbir S MEHTA
;
Arosho FERNANDO
;
Veronica FERGUSON
Author Information
- Publication Type:Case Reports
- MeSH: Aged; Cataract Extraction; adverse effects; Endophthalmitis; drug therapy; etiology; Fibrin; drug effects; Fibrinolytic Agents; therapeutic use; Humans; Male; Postoperative Period; Recombinant Proteins; therapeutic use; Tissue Plasminogen Activator; therapeutic use
- From:Annals of the Academy of Medicine, Singapore 2006;35(10):723-725
- CountrySingapore
- Language:English
-
Abstract:
INTRODUCTIONThe aim of this paper was to describe the use of r-TPA for fibrin clot dissolution following endophthalmitis.
CLINICAL PICTUREA 74-year-old man presented with painful loss of vision following routine uncomplicated cataract surgery.
TREATMENTHe underwent standard treatment for postoperative endophthalmitis but despite this, developed a dense fibrin clot. He underwent further intracameral injection of r-TPA.
OUTCOMEFollowing the injection, he had complete clot dissolution within 2 hours without any complications.
CONCLUSIONR-TPA may be used effectively in the treatment of fibrin clots secondary to endophthalmitis following cataract surgery.
