Risk factors of cognitive impairment after off-pump coronary artery bypass grafting
10.3760/cma.j.issn.0253-3758.2012.02.006
- VernacularTitle:非体外循环冠状动脉旁路移植术后认知功能障碍的影响因素
- Author:
Qin-Tao CUI
1
;
Qing-Lin FU
;
Pei-Li HAN
;
Jie ZHANG
Author Information
1. 新乡医学院附属第一医院
- Keywords:
Coronary disease;
Coronary artery bypass,off-pump;
Cognition disorders;
Risk factors
- From:
Chinese Journal of Cardiology
2012;40(2):104-107
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors of cognitive impairment after off-pump coronary artery bypass grafting (OPCABG).Methods A total of 102 patients [ male:82,age:(65.7 ± 7.1 ) years ]undergoing OPCABG in our hospital between January 2009 and December 2010 were divided into postoperative cognitive dysfunction (POCD) group and non-POCD group by the MMSE questionnaire survey conducted at 7 days pre- and post-operation respectively.Results The incidence of POCD was 48.0％ ( 49/102 ).Multivariate logistic stepwise regression analysis showed:advanced age (OR =1.32,95％ CI:1.10 - 1.46,P=0.002),smoking (OR=1.26,95％ CI:1.18-1.32,P=0.001),hypertension (OR =1.66,95％ CI:1.36 - 1.78,P =0.023),diabetes ( OR =1.62,95％ CI:1.02 - 2.84,P =0.032),stroke ( OR =3.32,95 ％ CI:1.68 - 6.49,P ＜ 0.001 ),mitral regurgitation ( OR =1.48,95 ％ CI:1.26 - 1.89,P ＜ 0.001 ),and time of wall clamp ( OR =4.84,95％ CI:1.08 - 7.28,P ＜ 0.001 ) were independent risk factors of POCD.Conclusion Advanced age,smoking,hypertension,diabetes,stroke,mitral regurgitation,and prolonged time of wall clamp are major risk factors for POCD in patients undergoing OPCABG.
