Quality of life change and its influencing factors in patients with acute coronary syndrome after drugeluting stent implantation
10.3760/cma.j.issn.0253-3758.2012.04.007
- VernacularTitle:急性冠状动脉综合征患者支架术后生命质量及其影响因素分析
- Author:
Chao XUE
1
;
Da-Yi HU
;
Yi-Hong SUN
;
Rong-Jing DING
;
Wei-Min WANG
;
Wen-Ling LIU
;
Cui-Lan LI
;
Lei LI
;
Yu CHEN
Author Information
1. 北京大学人民医院
- Keywords:
Coronary diseasc;
Stents;
Quality of life
- From:
Chinese Journal of Cardiology
2012;40(4):293-297
- CountryChina
- Language:Chinese
-
Abstract:
Objective To prospectively evaluate the change of quality of life in patients with acute coronary syndrome following percutaneous coronary intervention (PCI) with durg-eluting stents and explore the influencing factors of quality of life.Methods There hundred and thirty four consecutive patients with acute coronary syndrome receiving drug-cluting stents implantation between September 2008 and December 2009 were enrolled.Of them,two hundred and ninety three patients completed 36-item short form health survey at baseline and 6 months after PCI procedure.Change of quality of life and influencing factors on quality of life were analyzed.Results Compared with baseline,quality of life improved significantly after PCI in terms of both physical component summary and mental component summary [(51.07 ± 20.39 ) scores vs.(61.69 ± 19.73 ) scores and (63.27 ± 20.00) scores vs. (68.81 ± 18.71 ) scores,respectively; all P＜0.01]. Multiple linear regression analysis showed that female,diabetes and ST-segment elevation myocardial infarction were independent predictors of physical component summary improvements post PCI ( βvalues were -0.310,-3.880 and 1.302,respectively; P＜0.05 or P＜0.01 ).Previous PCI and diabetes were independent predictors of mental component summary improvements post PCI ( β values were -1.483 and -2.790,respectively; all P＜0.01).Conclusions Quality of life of acute coronary syndrome patients is significantly improved at 6 months after drug-eluting stents implantation.The predictors of physical quality of life improvement are female,diabetes,and ST-segment elevation myocardial infarction. Predictors of mental quality of life improvement are previous PCI and diabetes.
