Triterpenoid saponins from bark Mitragyna inermis.
- Author:
Zhi-hong CHENG
1
;
Bo-yang YU
;
Xiu-wei YANG
;
Jian ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Antineoplastic Agents, Phytogenic; pharmacology; Carcinoma, Hepatocellular; pathology; Humans; Liver Neoplasms; pathology; Mitragyna; chemistry; Plant Bark; chemistry; Plants, Medicinal; chemistry; Saponins; chemistry; isolation & purification; pharmacology; Tumor Cells, Cultured; drug effects
- From: China Journal of Chinese Materia Medica 2002;27(4):274-277
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the constituents of Mitragyna inermis that have an anti-tumor activity on Bel-7402 of hepatic carcinoma.
METHODThe compounds were isolated by column chromatography on silica gel, ODS, Sephadex LH-20 separately and their structures were elucidated by chemical and spectral technology.
RESULTThree quinovic acid glycosides, quinovic acid 3 beta-beta-D-glucopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-28-O-beta- D-glucopyranoside(I), quinovic acid 3 beta-O-beta-D-quinovopyranoside(II), quinovic acid 3 beta-O-beta-D-glucopyranoside(III), were obtained.
CONCLUSIONI, II were isolated from Mitragyna for the first time.
