Research progress in the relationship between heart development and cell apoptosis.
- Author:
Mengqian TANG
1
;
Xuehong LIU
Author Information
1. Medicine College, Shaoxing University, Shaoxing 312000, China.
- Publication Type:Journal Article
- MeSH:
Apoptosis;
genetics;
Gene Expression Regulation, Developmental;
Heart;
embryology;
Humans
- From:
Journal of Biomedical Engineering
2011;28(6):1257-1260
- CountryChina
- Language:Chinese
-
Abstract:
The development of heart is an accurate, coordinated process including primordial cardiac cell differentiation, migration, and multi-cell combination. This process is accompanied by cell apoptosis, and by a series of gene regulation. If gene gets out of regulation, abnormal cell apoptosis will occur, which will lead to abnormal development of embryonic heart, or even malformation. By studying gene expression on apoptosis, we investigated the relationship between apoptosis and embryonic heart development, clarified the relevant mechanism for the clinical diagnosis and treatment of heart diseases.
