Solitary Neurofibroma Occurred on the Eyelid Margin without Neurofibromatosis: A Case Report.
10.3341/jkos.2017.58.2.222
- Author:
Yeon Soo KANG
1
;
Won CHOI
;
Ga Eon KIM
;
Kyung Chul YOON
Author Information
1. Department of Ophthalmology, Chonnam National University Medical School, Gwangju, Korea. kcyoon@jnu.ac.kr
- Publication Type:Case Report
- Keywords:
Eyelid mass;
Neurofibroma;
Neurofibromatosis
- MeSH:
Biopsy;
Diagnosis, Differential;
Eosine Yellowish-(YS);
Eyelids*;
Hematoxylin;
Humans;
Korea;
Male;
Middle Aged;
Neurofibroma*;
Neurofibromatoses*;
Recurrence
- From:Journal of the Korean Ophthalmological Society
2017;58(2):222-225
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We report a rare case of solitary neurofibroma on the eyelid margin without neurofibromatosis. CASE SUMMARY: A 46-year-old male presented with a well-define small nodular lesion on the right upper eyelid margin that had not changed for 10 years. Surgical excision and biopsy were performed. Histological examination showed spindle-shaped cells in the fibrous stroma on hematoxylin & eosin staining, and immunohistochemical staining revealed S-100 protein-positive cells. Dermatologic, neurologic, and genetic evaluations showed no evidence of systemic neurofibromatosis. Six months after operation, there was no evidence of local recurrence. CONCLUSIONS: To the best of our knowledge, this is the first case of solitary neurofibroma involving the eyelid margin without neurofibromatosis in Korea. Neurofibroma should be considered in a differential diagnosis of eyelid mass and can be successfully managed with surgical excision.
