Chemical constituents from marine fungus Penicillium thomii.
- Author:
Ting JIANG
1
;
Li TIAN
;
Ai-hua GUO
;
Hong-zheng FU
;
Yue-hu PEI
;
Wen-han LIN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Molecular Conformation; Molecular Structure; Penicillium; chemistry; isolation & purification; Sea Anemones; microbiology; Xanthones; chemistry; isolation & purification
- From: Acta Pharmaceutica Sinica 2002;37(4):271-274
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo investigate the bioactive constituents from the mycelium of Penicillium thomii. Which isolated from Anemone collected in Qingdao beach.
METHODSThe constituents were separated by using various chromatography and the structures were identified on the basis of extensive spectral analysis.
RESULTSFive compounds, namely penicillixanthone A (I), p-methylbenzolic acid (II), 1-O-hexadecanoyl-2-O-(9-octadecenoyl)-3-O-(9, 12-octadecadienoyl) glycerol (III), 5 alpha, 8 alpha-epidioxy-24 zeta-methylcholesta-6, 22-dien-3 beta-ol (IV) and 1, 6, 8-trihydroxyl-3-methyl-9, 10-anthracenedione (V), were isolated from the mycelium of Penicillium thomii.
CONCLUSIONPenicillixanthone A is a new compound, while the others are isolated from Penicillium thomii for the first time.
