A new anthraquinone glycoside from the root of Rheum officinale Baill.
- Author:
Zheng-Xiang XIA
1
;
Zhong-Yan TANG
;
Rui AN
;
Ye CHEN
;
Yi-Zhu ZHANG
;
Xin-Hong WANG
Author Information
1. School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
- Publication Type:Journal Article
- MeSH:
Anthraquinones;
chemistry;
isolation & purification;
pharmacology;
Glycosides;
chemistry;
isolation & purification;
pharmacology;
Hep G2 Cells;
Humans;
Molecular Structure;
Plant Roots;
chemistry;
Plants, Medicinal;
chemistry;
Rheum;
chemistry
- From:
Acta Pharmaceutica Sinica
2012;47(9):1183-1186
- CountryChina
- Language:English
-
Abstract:
A new and a known anthraquinone glycosides were isolated from the ethanol extract of the roots of Rheum officinale Baill. The extract was purified by various chromatographies, such as silica gel, Sephadex LH-20, RP-C18 column chromatography and HPLC. Two compounds were identified by the spectroscopic techniques of NMR, MS, and chemical method. In addition, they were tested for their cytotoxic effects against HepG2 cell. Unfortunately, they showed no or weak activity.
