A new triterpenoid tetrasaccharide from the root of Scrophularia ningpoensis.
- Author:
Liu-qiang ZHANG
1
;
Fu-jiang GUO
;
Shun-chun WANG
;
Yi-ming LI
Author Information
1. School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
Glycosides;
chemistry;
isolation & purification;
Molecular Structure;
Plant Roots;
chemistry;
Plants, Medicinal;
chemistry;
Scrophularia;
chemistry;
Triterpenes;
chemistry;
isolation & purification
- From:
Acta Pharmaceutica Sinica
2012;47(10):1358-1362
- CountryChina
- Language:English
-
Abstract:
A new oleanane-type triterpenoid glycoside, 3beta-O-(f-D-xylopyranosyl-(1-->2)-[beta-D-glucopyranosyl (1-->4)-beta-D-glucopyranosyl-(1 -->3)]-beta-D-fucopyranosyl-11, 13(18) diene-olean-23alpha, 28 diol (1), along with three known phenylethyl glycosides (2-4), was isolated from the root of traditional Chinese medicine Scrophularia ningpoensis. Among them, compounds 2 and 3 were obtained from Scrophularia genus for the first time. The structure of compound 1 was elucidated on the basis of spectroscopic method including 1D, 2D NMR and HR-ESI-MS.
