Peritonitis in Children Undergoing Peritoneal Dialysis: 10 Years' Experience in a Single Center.
- Author:
Se Eun LEE
1
;
Kyoung Hee HAN
;
Yun Hye JUNG
;
Hyun Kyung LEE
;
Hee Gyung KANG
;
Hae Il CHEONG
;
Il Soo HA
Author Information
1. Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. ilsooha@snu.ac.kr
- Publication Type:Original Article
- Keywords:
Peritoneal dialysis;
Peritonitis;
Children
- MeSH:
Acinetobacter;
Ceftazidime;
Child;
Fungi;
Humans;
Incidence;
Medical Records;
Peritoneal Dialysis;
Peritonitis;
Pseudomonas;
Retrospective Studies;
Staphylococcus
- From:Journal of the Korean Society of Pediatric Nephrology
2010;14(2):174-183
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The organisms causing peritonitis and their antibiotic sensitivities vary in different regions and centers, and these data are necessary to establish regional treatment guidelines. The aim of this study was to investigate the changes in incidence and characteristics of the organisms that cause peritonitis in children undergoing peritoneal dialysis (PD) during recent 10 years. METHODS: We retrospectively collected and analyzed the data from medical records of 110 children on PD during the period from 2000 to 2010. RESULTS: One hundred and forty episodes of peritonitis have occurred in 57 patients. The overall incidence of peritonitis was 0.43 episodes/patient.year, and similar incidence have been maintained since 2003. Sixty percent of the patients experienced peritonitis within 1 year of PD, and all patients commencing PD in infancy experienced peritonitis. Gram positive (G (+)), gram negative (G (-)) organisms and fungi were cultured in 58%, 38%, and 4.1% respectively and cultures were negative in 13.6%. Staphylococcus was the most common G (+) organism, and Pseudomonas and Acinetobacter were 2 most frequent G (-) organisms isolated. Fifty-six percent of the G (+) organisms were sensitive to first generation cephalosporin and 91% of G (-) pathogens were sensitive to ceftazidime. Methicillin-resistance rate was not higher in children less than 2 years of age than in those more than 2 years. CONCLUSION: An additional breakthrough has to be made to further reduce the incidence of peritonitis. Treatment guideline customized for peritonitis in Korean children on PD need to be established through a nationwide co-work.
