Effect of initial periodontal therapy on chronic periodontitis patients with stable coronary heart disease
10.3760/cma.j.issn.1002-0098.2009.06.010
- VernacularTitle:伴冠心病牙周炎患者牙周基础治疗的临床疗效观察
- Author:
Xiang-Qing DUAN
1
;
Xiang-Ying OUYANG
;
Rong HU
Author Information
1. 首都医科大学附属北京安贞医院
- Keywords:
Periodontitis;
Coronary disease;
C-reactive protein;
Initial periodontal therapy
- From:
Chinese Journal of Stomatology
2009;44(6):351-354
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical results of initial periodontal therapy on chronic periodontitis patients with stable coronary heart disease. Methods Thirty-two chronic periodontitis patients with stable coronary heart disease were included in this prospective study. All subjects received oral hygiene instruction, scaling and root planing and clinically monitored for 3 months. The clinical parameters,including plaque index(PLI) , probing depth (PD) , attachment loss(AL) and bleeding index(BI) , were recorded at baseline and 3 months after treatment. Serum levels of high-sensitivity C-reactive protein (hs-CRP) , cholesterol (CHO) , triglyceride (TG) , high-density lipoprotein (HDL) , low-density lipoprotein(LDL) and glucose (GLU) were also measured. Results At 3 months after initial periodontal therapy, the mean PD of patients reduced from(3.95±0.15)mm to(2.93±0.21)mm(P＜0.01),the mean AL from(3.08±0.43)mm to(2.43±0.37)mm(P＜0.01),the percentage of sites with PD≥5 mm from (22.37±6.88)%to(3.00±1.80)%(P＜0.01).hs-CRP significantly decreased at 3 months after treatment compared with baseline[(2.71±2.69)mg/L vs.(1.99±2.14)mg/L,P＜0.05].CHO,TG,HDL,LDL and GLU decreased slightly(P＞0.05).Conclusions Initial periodontal therapy is effective for chronic periodontitis patients with stable coronary heart disease.After initial periodontal therapy,periodontal parameters improved significantly and serum levels of hs-CRP decreased.
