Effect of Yupingfeng on the level of salivary epidermal growth factor in oral lichen planus.
- Author:
Yuan FAN
1
;
Juan-Yong XU
;
Qing-Lan LIU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Case-Control Studies; Drugs, Chinese Herbal; pharmacology; Epidermal Growth Factor; metabolism; Female; Humans; Lichen Planus, Oral; metabolism; Male; Middle Aged; Saliva; metabolism
- From: Chinese Journal of Stomatology 2009;44(7):392-394
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo examine the effect of mouthwash Yupingfeng on the level of salivary epidermal growth factor (sEGF) in oral lichen planus (OLP).
METHODSThe level of sEGF was measured by radioimmunoassay with ligand 125I-EGF. The saliva samples were taken from the normal control group and the OLP patients before and after treatment with Yupingfeng.
RESULTSThe levels of sEGF in OLP patients before treatment with Yupingfeng were (4.09 +/- 3.64) microg/L, which was significantly higher than that in normal control [(2.15 +/- 1.62) microg/L, P = 0.013], and (2.57 +/- 1.19) microg/L after treatment,which was significantly lower than before treatment (P = 0.05).
CONCLUSIONSYupingfeng can modulate the level of sEGF in OLP patients.
