Evaluation of fluorodeoxylucose-position-emission tomography-computer tomography imaging on head and neck squamous cell cardnomas including primary tumors and lymph node metastases

VernacularTitle:氟脱氧葡萄糖-正电子发射体层摄影术-CT判断头颈部鳞状细胞癌及其淋巴结转移的临床价值
Author: Sheng-Jiao LI ¹ ; Wei GUO ; Jian-Xing LIAO ; Guo-Xin REN
Author Information

1. 同济大学附属口腔医院口
Keywords: Carcinoma; squamous cell; Positron-emission tomography; Tomography; X-ray computed; Fluorodeoxyglucose F18
From: Chinese Journal of Stomatology 2009;44(10):601-605
CountryChina
Language:Chinese
Abstract: Objective To evaluate ~(18)F-fluorodeoxylucose-position-emission tomography-computer tomography imaging(~(18)F-FDG-PET-CT)on head and neck squamous cell carcinoma(HNSCCA)and lymph node metastasis.Methods ~(18)F-FDG-PET-CT imaging of 20 patients with HNSCCA was evaluated retrospectively.Results A11 the primary tumors were correctly diagnosed by ~(18)F-PET-CT imaging and SUV_(avg) of the primary tumors was(6.22±2.20).All the sensitivity,specificity,positive predictive value and the negative predictive value were 100%.In detecting lymph node metastasis,the sensitivity was 51%,specificity 97.7%,false positive rate 2.3%,false negative rate 49%,positive predictive value 82%,and negative predictive value 91.2%. Conclusions ~(18)F-FDG-PET-CT imaging was valuable in detecting HNSCCA and lymph node metastasis.SUV was helpful for differential diagnosis between benign or malignant tumors but it needs further study to determine the cutoff SUV for differentiating lymph node etastasis.