Wnt signaling pathways and osteoarthritis.
- Author:
Ning-Yang GAO
1
;
Yue-Long CAO
;
Ting LIU
;
Jian PANG
;
Hong-Sheng ZHAN
;
Yin-Yu SHI
Author Information
1. Institution of Orthopaedics, Academy of TCM of Shanghai, Shanghai 201203, China. sapphire512@163.com
- Publication Type:Journal Article
- MeSH:
Animals;
Chondrocytes;
metabolism;
pathology;
Humans;
Osteoarthritis;
metabolism;
pathology;
Signal Transduction;
Wnt Proteins;
metabolism
- From:
China Journal of Orthopaedics and Traumatology
2010;23(4):320-323
- CountryChina
- Language:Chinese
-
Abstract:
The Wnt signaling exists in every kinds of species and regulates a variety of biological processes including cell fate, proliferation and function, immunity, stress, apoptosis and so on. During the researching, Wnt signaling also plays an important role in chondrocyte differentiation and maturation. So it has been the new spot in pathogenesis of osteoarthritis study.