Advance in study of vascular endothelial cell and smooth muscle cell co-culture system.
- Author:
Yujie LI
1
;
Qing YANG
;
Xiaogang WENG
;
Ying CHEN
;
Congxiao RUAN
;
Dan LI
;
Xiaoxing ZHU
Author Information
1. Institute of Chinese Materia Medica, China Academy of Chinese Medicinal Sciences, Beijing 100700, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Coculture Techniques;
methods;
Endothelial Cells;
cytology;
metabolism;
Humans;
Muscle, Smooth, Vascular;
cytology;
Myocytes, Smooth Muscle;
cytology;
metabolism
- From:
China Journal of Chinese Materia Medica
2012;37(3):265-268
- CountryChina
- Language:Chinese
-
Abstract:
The interactions between endothelial cells (EC) and smooth muscle cells (SMC) contribute to vascular physiological functions and also cause the occurrence and development of different kinds of diseases. Currently, EC-SMC co-culture model is the best way to study the interactions between the two kinds of cells. This article summarizes existing EC-SMC co-culture models and their effects on the structure and functions of the two kinds of cells. Microscopically speaking, it provides a basis for in-depth studies on their interactions as well as a reference for the establishment of in vitro EC-SMC co-culture system that is closer to organic physiology or pathology state.
