The Diagnostic Value of Serum Monocyte Percentage in Young Infants Suspected of Meningitis.
- Author:
Ji Ho LEE
1
;
Won Seop KIM
;
Yong Dae KIM
;
Ji Hyuk LEE
Author Information
1. Department of Pediatrics, College of Medicine, Chungbuk National University, Cheongju, Korea. jihugy@chungbuk.ac.kr
- Publication Type:Original Article
- Keywords:
Meningitis;
Infant;
Monocyte
- MeSH:
Chungcheongbuk-do;
Humans;
Infant*;
Meningitis*;
Monocytes*;
Spinal Puncture
- From:
Journal of the Korean Child Neurology Society
2013;21(3):152-161
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To avoid a unnecessary lumbar puncture, we tried to find a useful tool for prediction of meningitis in infants. METHODS: One hundred and twenty four patients underwent a lumbar puncture at Chungbuk National University Hospital from Jan 1, 2011 to Dec 31, 2011. We divided them into 2 groups by the evidence of meningitis, and compared laboratory findings and clinical manifestations. RESULTS: There were 30 patients for meningitis group and 94 patients for control group. Meningitis group revealed lower serum monocyte percentage (meningitis group 10.1+/-4.7%, control group 12.2+/-5.0%, P=0.049) than control group. Other laboratory findings and clinical manifestations showed no statistically significant differences between two groups. CONCLUSION: Serum monocyte percentage could help to predict meningitis in young infants, but it is not enough to replace a lumbar puncture. We therefore think that it requires a more accurate non-invasive diagnostic tool to detect meningitis.
