The radiation-induced jaw osteosarcoma: CT imaging features
10.3760/cma.j.issn.1002-0098.2014.01.003
- VernacularTitle:放射性颌骨骨肉瘤:CT影像学表现
- Author:
Shaoying WANG
1
;
Zilai PAN
;
Huimin SHI
;
Pingzhong WANG
Author Information
1. 上海交通大学医学院附属第九人民医院口腔医学院放射科上海市口腔医学研究所上海市口腔医学重点实验室 200011
- Keywords:
Osteosarcoma;
Jaw;
CT imaging
- From:
Chinese Journal of Stomatology
2014;49(1):5-8
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the CT features of radiation-induced jaw osteosarcoma(RIJOS) developed after therapeutic irradiation for a variety of nonosseous lesions.Methods The demographic and CT findings of thirteen patients with RIJOS were reviewed retrospectively.Observation items included location,bone destruction,mineralized tumor matrix,periosteal reaction,soft tissue extension and calcification.Of the thirteen patients,twelve were male and one was female.The mean age was 48 years (range:29-68 years).Five patients had tumors in the maxilla and eight in the mandible.All the patients underwent tumor resection.Results The latent period before development of RIJOS ranged from 3.5 to 14 years (mean,11 years).In all thirteen patients,eight tumors were osteoblastic,with one osteolytic and four mixed lesions.Osteoid tumor matrix mineralization was present in twelve patients.Periosteal reaction was identified in 11 cases.Soft-tissue extension was present in all patients beyond the area of bone destruction.Conclusions The characteristic CT imaging of RIJOS showed the bone destruction associated with a large number of mineralized tumor matrix and significant soft tissue extension in the original radiation field after radiotherapy.CT findings could play an important role in identifying the tumor and pre-operative assessment.
