- Author:
Sung Woo CHO
1
;
Yun Jeong KANG
;
Tae Hoon KIM
;
Sung Kyun CHO
;
Mee Won HWANG
;
Won CHANG
;
Kun Joo RHEE
;
Byung Ok KIM
;
Choong Won GOH
;
Kyoung Min PARK
;
Jeong Hoon KIM
;
Young Sup BYUN
;
Young Jin YUH
Author Information
- Publication Type:Case Report
- Keywords: Lymphoma, Large B-cell, Diffuse; Cardiac tumor; Atrioventricular block
- MeSH: Antibodies, Monoclonal, Murine-Derived; Atrioventricular Block; Biopsy; Drug Therapy, Combination; Dyspnea; Electrocardiography; Follow-Up Studies; Heart Neoplasms; Humans; Lymphoma; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Male; Sweat; Sweating; Thorax; Vincristine; Rituximab
- From:Korean Circulation Journal 2010;40(2):94-98
- CountryRepublic of Korea
- Language:English
- Abstract: Primary cardiac lymphomas (PCL) are extremely rare. Clinical manifestations may be variable and are attributed to location. Here, we report on a case of PCL presenting with atrioventricular (AV) block. A 55 year-old male had experienced chest discomfort with unexplained dyspnea and night sweating. His initial electrocardiogram (ECG) revealed a first degree AV block. Along with worsening chest discomfort and dyspnea, his ECG changed to show second degree AV block (Mobitz type I). Computed tomography (CT) scan showed a cardiac mass (about 7 cm) and biopsy was performed. Pathologic finding confirmed diffuse large B-cell lymphoma. The patient was treated with multi-drug combination chemotherapy (R-CHOP: Rituximab, cyclophoshamide, anthracycline, vincristine, and prednisone). After treatment, ECG changed to show normal sinus rhythm with complete remission on follow-up CT scan.