Lymphadenectomy adjacent to inferior mesenteric artery root during radical operation and prognosis in rectal cancer.

Peng Deng; Dong-qiu Dai; Jun-qing Chen; Hui-mian XU; Shu-bao Wang; Ji-xian Shan

Return

Lymphadenectomy adjacent to inferior mesenteric artery root during radical operation and prognosis in rectal cancer.

Author: Peng DENG ¹ ; Dong-Qiu DAI ; Jun-Qing CHEN ; Hui-Mian XU ; Shu-Bao WANG ; Ji-Xian SHAN
Author Information

1. Department of Oncology Surgery, The First Hospital, China Medical University, Shenyang 110001, China.
Publication Type:Journal Article
MeSH: Adult; Aged; Aged, 80 and over; Female; Humans; Lymph Node Excision; methods; mortality; Lymph Nodes; surgery; Lymphatic Metastasis; Male; Mesenteric Artery, Inferior; surgery; Middle Aged; Prognosis; Rectal Neoplasms; mortality; pathology; surgery; Survival Rate; Treatment Outcome
From: Chinese Journal of Gastrointestinal Surgery 2008;11(3):241-245
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo investigate the effect of lymphadenectomy adjacent to inferior mesenteric artery root on the prognosis of rectal cancer.
METHODSClinicopathological data of 260 cases with rectal cancer undergone radical operation were analyzed retrospectively. The patients were divided into two groups. Group D(2): the lymph nodes adjacent to mesenteric artery root were not excised (n=188). Group D(3): the lymph nodes adjacent to mesenteric artery root were excised (n=72). Prognosis of two groups was compared during the follow-up period.
RESULTSIn group D(2), the 1-, 3-, 5-year total survival rates (TS) were 97.3%, 87.2% and 77.1%, and tumor-free survival rates (TFS) were 93.1%, 83.0% and 76.8% respectively. In group D(3 ), the 1-, 3-, 5-year total survival rates (TS) were 94.4%, 79.2% and 73.6%, and tumor-free survival rates (TFS) were 86.1%, 76.4% and 71.0% respectively. The differences of TS and TFS between two groups were not significant according to Kaplan-Meier analysis (P>0.05). Multivariate analysis revealed that the excision of lymph nodes adjacent to mesenteric artery root was not statistically correlated with the recurrence, metastasis and survival time after radical operation of rectal cancer.
CONCLUSIONExcision of lymph nodes adjacent to inferior mesenteric artery root has no significant impact on prognosis and it is unnecessary in the radical operation of rectal cancer.