Clinical Trials of Frason on Various Dermatosis.
- Author:
Jong Myung HYUN
;
Nan Hee LEE
;
Yang Ja PARK
;
Jin Tack KIM
- Publication Type:Original Article ; Clinical Trial
- MeSH:
Anti-Bacterial Agents;
Communicable Diseases;
Dermatitis;
Dermatitis, Atopic;
Dermatitis, Contact;
Dermatitis, Seborrheic;
Desoximetasone;
Eczema;
Framycetin;
Humans;
Intertrigo;
Neurodermatitis;
Otitis;
Pruritus;
Skin;
Skin Diseases*;
Streptomyces;
Sudden Infant Death
- From:Korean Journal of Dermatology
1977;15(2):191-195
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Esperson(R), a new topical steroid ointment containing 0. 05% 17-Desoxymethasone,. was used in several kinds of dermatoses. Framycetin which was isolated and uientified by the research organisation of Roussel Laboratories (SOFRAPEN) in 1950 from culture broths of a strain of Streptomyces species is a wide spectrum antibiotics on various bacterial infectious diseases. Total 50 patients including 10 cases of 2ndary infected Atopic dermatitis, 10 of infected Contact dermatitis, 6 of infected Seborrheic dermatitis, 7 of infected Neurodermatitis, 3 of infected Chronic dermatitis, 5 of lmpetigo, 2 of infected Nummular eczema, 2 of infected Infantile ecze;na, 1 of infected Intertrigo, 1 of Eczematoid Otitis extema, 1 of 2nd degree Bum, 1 of infected Pruritis ani, 1 of infeeted 1nsect bite. were treated with Frason(R) (0.05% 17-desoxymethasone & 0.5% Framycetin combination). Among these 50 patiants, we observed excellent effects in 7 patients (14%), good effect in 29 patients (58%), fair effect in 10 patients (20%), Totally 36 patients (72%) revealed excellent to good therapeutic effects on their skin conditione after unoccluded application of Frason(R). 3 times daily for about 14 days. There was no sid ffect in all subjects after application of Esperson-F.
