Study on the prevalence of acute flaccid paralysis and hand foot mouth disease in Beijing 2006-2008

VernacularTitle:北京市2006-2008年急性弛缓性麻痹与手足口病关联分析
Author: Ming LUO ¹ ; Cheng GONG ; Tie-Gang ZHANG
Author Information

1. 疾病预防控制中心免疫预防所
Keywords: Hand foot mouth disease; Acute flaccid paralysis; Enterovirus 71
From: Chinese Journal of Epidemiology 2011;32(7):681-684
CountryChina
Language:Chinese
Abstract: Objective To study the prevalence of acute flaccid paralysis(AFP)and hand foot mouth disease(HFMD)in Beijing,from 2006-2008.Methods Data on AFP and HFMD was analyzed epidemiologically,during 2006-2008 in Beijing.All the specimens from AFP cases were isolated and identified by RD and L20B cell and all of non-polio enterovirus(NPEV)cases were assayed by HFMD real-time PCR kit.The relationship between AFP and HFMD was analyzed.Results During 2006-2008,the number of AFP case in Beijing increased from 108 to 177 while the NPEV isolation rate increased from 11.11%to 20.34%and the positive rate of enterovirus 71(EV71)and/or coxsackie virus A16(Cox A16)increased from 0.93%to 10.17%.Conclusion The prevalence of HFMD caused by EV71 and/or Cox A16 might have contributed to the increase of AFP cases in Beijing.