Study on preparation of beta-cyclodextrin inclusion complex of volatile oil in xiongdan xiaoyan capsules.
- Author:
Xiong-liang XU
1
;
Zhi-rong ZHANG
;
Zu-xing HE
;
Guo-qing HUANG
;
Dong RAN
Author Information
- Publication Type:Journal Article
- MeSH: Angelica; chemistry; Capsules; Drug Carriers; Drug Combinations; Drug Stability; Drugs, Chinese Herbal; administration & dosage; isolation & purification; Mentha; chemistry; Oils, Volatile; administration & dosage; isolation & purification; Plants, Medicinal; chemistry; Saururaceae; chemistry; Technology, Pharmaceutical; methods; Ultrasonics; beta-Cyclodextrins
- From: China Journal of Chinese Materia Medica 2004;29(7):644-646
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study optimum inclusion conditions for volatile oil from three medicinal slices in Xiongdan Xiaoyan capsules.
METHODSaturated water solution method (agitation method), ultrasonic method and rubbing method were studied and compared. The preparation conditions of ultrasonic method were investigated by the orthogonal test.
RESULTThe optimum inclusion conditions of ultrasonic method were established.
CONCLUSIONThe ultrasonic method can be used for production of inclusion complex in the factory with high inclusion rate and was effectiveness.