Study on releasing rate of chrysophanol from Ruyi Jinhuang plaster.
- Author:
Ping MAO
1
;
Jia XU
;
Yun-Mine WU
Author Information
- Publication Type:Journal Article
- MeSH: Administration, Cutaneous; Animals; Anthraquinones; metabolism; Curcuma; chemistry; Drug Combinations; Drugs, Chinese Herbal; isolation & purification; pharmacokinetics; Female; Guinea Pigs; Male; Phellodendron; chemistry; Plants, Medicinal; chemistry; Rheum; chemistry; Skin; metabolism; Skin Absorption
- From: China Journal of Chinese Materia Medica 2004;29(8):746-816
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the releasing rate of chrysophanol from Ruyi Jinhuang plaster.
METHODBased on the detecting methods of releasing rate and residual dosage applied in (Pharmacopoeia of P. R. C) (2000 edition), the contents of chrysophanol were detected by HPLC.
RESULTChrysophanol in Ruyi Jinhuang plaster could well be released from plaster and to form medicinal concentration gradient.
CONCLUSIONChrysophanol in Ruyi-Jinhuang plaster can possibly be absorbed by skin.