Isolation and elucidation of antioxidant constituents from acetone extract in root of Scutellaria rehderiana.

Author: Ya-lun SU ¹ ; Yu HUANG ; Zhen-yu CHEN
Author Information

1. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. suyalun@imm.ac.cn
Publication Type:Journal Article
MeSH: Antioxidants; chemistry; isolation & purification; pharmacology; Flavanones; chemistry; isolation & purification; pharmacology; Flavonoids; chemistry; isolation & purification; pharmacology; Plant Roots; chemistry; Plants, Medicinal; chemistry; Scutellaria; chemistry
From: China Journal of Chinese Materia Medica 2004;29(9):863-864
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo isolatate and elucidate the antioxidant constituents from acetone extract of Scutellaria rehderiana.
METHODChemical constituents were isolated by several column chromatographies and their structures were elucidated on the basis of standard compounds and spectral analysis.
RESULTFive compounds, oroxylin A, wogonin, baicalein, ganhuangenin, ganhuangemin were isolated from acetone extract of S. rehderiana. Baicalin was obtained from methanol extract of S. rehderiana.
CONCLUSIONGanhuangemin was isolated from the plant for the first time. Baicalein and ganhuangenin have stronger antioxidant activity than that of BHT (butylated hydroxytoluene).