Study on the compatibility of composite herbal medicines of the Zishen pill.
- Author:
Rong-hua DAI
1
;
Yuan-yuan ZHANG
;
Kai-shun BI
Author Information
- Publication Type:Journal Article
- MeSH: Anemarrhena; chemistry; Animals; Anti-Inflammatory Agents, Non-Steroidal; pharmacology; Carbon; pharmacokinetics; Cinnamomum; chemistry; Drug Combinations; Drug Interactions; Drugs, Chinese Herbal; isolation & purification; pharmacology; Ear; pathology; Ear Diseases; pathology; Edema; pathology; Male; Metabolic Clearance Rate; drug effects; Mice; Phellodendron; chemistry; Plants, Medicinal; chemistry
- From: China Journal of Chinese Materia Medica 2004;29(9):897-899
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the compatibility of composite herbal medicines of the Zishen pill.
METHOD50% ethanol extract test solution of the different combinations of composite herbal medicines of the Zishen pill were prepared. Pharmacologic experiments, such as anti-inflammatory, carbon particle clearance of RES were carried out with the solutions, and the corresponding pharmacological data were obtained. Variance analysis, canonical correlation and stepwise regression analysis were applied to interrelate the amount of each drug and the pharmacological data.
RESULTThe results confirmed that Huangbo and Zhimu were the basis, while Rougui was the corrigent, which was conformed to the theory of TCM.
CONCLUSIONThis study provides a significant try for studying the compatibility of composite herbal medicines.
