Study of stinging crystals in tian nanxing.
- Author:
Yan HE
1
;
Xue-feng FENG
;
Jie SUN
Author Information
- Publication Type:Journal Article
- MeSH: Acetic Acid; Alum Compounds; Animals; Calcium Oxalate; chemistry; isolation & purification; toxicity; Conjunctival Diseases; chemically induced; Crystallization; Dose-Response Relationship, Drug; Edema; chemically induced; Hot Temperature; Pinellia; chemistry; Plants, Medicinal; chemistry; Rabbits; Rhizome; chemistry; Technology, Pharmaceutical; methods
- From: China Journal of Chinese Materia Medica 2003;28(11):1015-1018
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo test whether the raphides in Tian Nanxing (Pinellia pedatisecta Schott) caused irritation.
METHODScan Electron Microscope and Microscope Oberservation; Animal experimental study.
RESULTThrough the comparision of unprocessed Tian Nanxing to processed ones which included 36 h, 72 h, 120 h processed samples, the great modifications in the structure of raphides, especially for the ones with barbs in the processed samples was observed with time course study. A further animal experimental study went to show that the rate of change for raphides with barbs existed a dose-reponse relationship to irritation.
CONCLUSIONInvestigations of the causes of these reactions showed that raphides of calcium oxalate are, at least in part, responsible for the Tian Nanxing's irritation.
