Determination of tetrahydrofuran in urine by headspace solid-phase microextraction and gas chromatography.
- Author:
Zhi-hui HAN
1
;
Sheng FU
;
Ke-ping YU
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, Gas; methods; Furans; urine; Humans; Occupational Exposure; analysis; Solid Phase Microextraction; methods
- From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2011;29(2):150-151
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEHeadspace solid-phase microextraction (HS-SPME) was used pre-concentration procedure for the determination of tetrahydrofuran in urine by gas chromatography with hydrogen flame detector.
METHODSSeveral parameters controlling SPME was studied and optimised: SPME fiber, extraction time and extraction temperature, desorption time and desorption temperature.
RESULTSUnder optimal conditions, the correlation coefficient was 0.9998 and good recoveries (range from 93.0% ∼ 100.8%) were achieved, the detection limit was 0.5 µg/L.
CONCLUSIONThe method can be applied to the determination of trace amount of tetrahydrofuran in urine.
