Risk factors of post-asphyxial multiple organ dysfunction in neonates.
- Author:
Jun-Yan LIU
1
;
Tao XIONG
;
Hong FENG
;
Yi QU
;
Qiang-Hua YE
;
De-Zhi MU
Author Information
- Publication Type:Journal Article
- MeSH: Asphyxia Neonatorum; complications; Female; Humans; Infant, Newborn; Logistic Models; Male; Multiple Organ Failure; etiology; prevention & control; Risk Factors
- From: Chinese Journal of Contemporary Pediatrics 2011;13(12):940-943
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the risk factors related to post-asphyxial multiple organ dysfunction (PA-MOD) in neonates.
METHODSA total of 397 neonates with birth asphyxia were enrolled from January 2009 to December 2010.The patients were divided into PA-MOD group (n=179) and non-PA-MOD group (n=218). The risk factors of PA-MOD were retrospectively studied.
RESULTSMultivariate logistic regression analysis showed that severe asphyxia, fetal distress, abnormal labor, and decreased amniotic fluid were the risk factors for PA-MOD among the neonates. Spearman rank correlation analysis showed that the number of the involved organs increased along with the increase of age at admission (P<0.05) and with the decrease of gestational age and birth weight (P<0.05).
CONCLUSIONSThe efforts should be made to enhance perinatal care for neonates, especially for preterm infants and low-birh-weight infants, to decrease the incidence of MOD.
