Two Cases of Kyrle's Disease.
- Author:
Jeong Bin YOON
1
;
Nack In KIM
Author Information
1. Department of Dermatology, College of Medicine, Kyung Hee University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Kyrle's disease
- MeSH:
Aged;
Basophils;
Diabetes Mellitus;
Humans;
Kidney Failure, Chronic;
Lower Extremity;
Male;
Middle Aged
- From:Korean Journal of Dermatology
1999;37(12):1808-1812
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kyrle's disease is a rare disorder characterized by hyperkeratotic papules containing a central, cone-shaped plug on the extensor surface of the extremites. We describe two cases of Kyrle's disease. The first case is 65-year-old male patient. He had multiple pruritic hyperkeratotic papules with a central plug on both lower extremities. He has suffered from Diabetes mellitus for 20 years. The second case is 54-year-old male patient. He had multiple pruritic hyperkeratotic papules with a central plug on the back, upper and lower extremities. He has been suffered from Diabetes mellitus for 20 years and chronic renal failure for 6 months. Histopathologic findings showed central epidermal invagination filled with heavy keratotic, partly parakeratotic plug and basophilic debries. Many vacuolated cells and a few dyskeratotic cells were seen below the keratotic plug.