Value of combined CT coronary angiography and adenosine stress myocardial perfusion scintigraphy for diagnosis of coronary artery disease.
- Author:
Qi WANG
1
;
Lu-Yue GAI
;
Yun-Dai CHEN
;
Zhi-Guo WANG
;
Bin FENG
;
Zhi-Wei GUAN
;
Bai-Xuan XU
;
Wei DONG
;
Li YANG
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Coronary Angiography; methods; Coronary Artery Disease; diagnosis; diagnostic imaging; Female; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Predictive Value of Tests; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed
- From: Chinese Journal of Cardiology 2011;39(3):233-237
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the accuracy and feasibility of combination of CT coronary angiography (CTCA) and adenosine stress myocardial perfusion scintigraphy (MPS) for diagnosis of coronary artery disease (CAD).
METHODSCTCA, MPS were performed in 105 patients with suspected or diagnosed CAD within 4 weeks before coronary angiography (CAG) examination.
RESULTSThe sensibility, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy were 97.1%, 75.0%, 88.2%, 93.1% and 89.5%, respectively, for CTCA; 79.7%, 63.9%, 80.9%, 62.2% and 74.3%, respectively, for MPS and 97.2%, 98.5%, 98.5%, 89.7% and 95.2%, respectively, for CTCA + MPS.
CONCLUSIONCombination of CTCA and adenosine stress MPS, which provided both anatomical and functional information of coronary vessels, could significantly increase the specificity and PPV of diagnosing CAD with CTCA.