Value of combined CT coronary angiography and adenosine stress myocardial perfusion scintigraphy for diagnosis of coronary artery disease

VernacularTitle:CT冠状动脉造影结合腺苷负荷核素心肌灌注显像诊断冠心病的应用价值
Author: Qi WANG ¹ ; Lu-Yue GAI ; Yun-Dai CHEN ; Zhi-Guo WANG ; Bin FENG ; Zhi-Wei GUAN ; Bai-Xuan XU ; Wei DONG ; Li YANG
Author Information

1. 解放军总医院
Keywords: Coronary artery disease; Tomography,X-ray computed; Coronary angiography; Radionuclide imaging
From: Chinese Journal of Cardiology 2011;39(3):233-237
CountryChina
Language:Chinese
Abstract: Objective To assess the accuracy and feasibility of combination of CT coronary angiography (CTCA) and adenosine stress myocardial perfusion scintigraphy (MPS) for diagnosis of coronary artery disease (CAD). Methods CTCA, MPS were performed in 105 patients with suspected or diagnosed CAD within 4 weeks before coronary angiography (CAG) examination. Results The sensibility,specificity, positive predictive value ( PPV ), negative predictive value ( NPV ) and accuracy were 97. 1%,75.0%, 88.2%, 93.1% and 89. 5%, respectively, for CTCA; 79.7%,63.9%,80.9%,62.2% and 74. 3%, respectively, for MPS and 97. 2% ,98. 5% ,98. 5% ,89. 7% and 95.2%, respectively, for CTCA +MPS. Conclusion Combination of CTCA and adenosine stress MPS, which provided both anatomical and functional information of coronary vessels, could significantly increase the specificity and PPV of diagnosing CAD with CTCA.