Low ankle brachial index and risk of death: a meta-analysis.

Author: Ying DONG ¹ ; Jin-Ming YU ; Da-Yi HU
Author Information

1. Clinical Research Institute and Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China.
Publication Type:Journal Article
MeSH: Ankle Brachial Index; Cause of Death; Cohort Studies; Humans; Risk Assessment; Risk Factors
From: Chinese Journal of Cardiology 2011;39(3):259-261
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo evaluate the association between low ankle brachial index and risk of death.
METHODSRelated cohort studies in the past 12 years were collected. Heterogeneity was analyzed with χ(2) and I(2). Pooled hazard ratio (HR) as the effect indicator and 95% confidence interval (CI) were used to estimate the association of low ankle brachial index and risk of death by fixed effect model (inverse variance method).
RESULTSA total of 8 studies were included with sum sample size of 30 029. In heterogeneity analysis, χ(2) was 5.46, I(2) was 0.0%, and P was 0.604. Meta-analysis resulted in pooled HR of 1.69 (95%CI: 1.55 - 1.84).
CONCLUSIONLow ankle brachial index is associated with increased risk of death.