Clinical characteristics and outcome of 32 patients with long-QT syndrome accompanied with torsade de pointes.
- Author:
Cui-hong HOU
1
;
Jing-tao ZHANG
;
Xiao-xing ZHANG
;
Ke-ping CHEN
;
Wei HUA
;
Shu ZHANG
;
Jie-lin PU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Female; Follow-Up Studies; Humans; Long QT Syndrome; complications; therapy; Male; Middle Aged; Pacemaker, Artificial; Torsades de Pointes; complications; therapy; Treatment Outcome; Young Adult
- From: Chinese Journal of Cardiology 2011;39(4):297-300
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo summarize the clinical characteristics and outcome of patients with long-QT syndrome (LQTs) accompanied with torsade de pointes.
METHODSThirty-two eligible patients were included in this study. Clinical and electrocardiographic data were analyzed and telephone or out-patient follow-up were made in all patients.
RESULTSThere were 15 patients with inherited LQTs (h-LQTs) and 17 patients with acquired LQTs (a-LQTs). There are more women (n = 24) than men (n = 8). β blockers, potassium and magnesium supplement were the basic therapy for h-LQTs patients, bivent pacemaker was implanted in 2 patients and implantable cardioverter defibrillator was implanted in 5 patients. Ventricular tachyarrhythmias and syncope occurred in 4 patients during (39.4 ± 25.1) months follow-up. In 17 a-LQTs patients, one patient with dilated cardiomyopathy died suddenly and another patient with implanted cardioverter defibrillator experienced one ventricular tachycardia during (30.9 ± 13.3) months follow-up.
CONCLUSIONSThe prognosis in h-LQTs and a-LQTs patients with structure heart disease is poor. ICD or CRT-D therapy is suggestive for a-LQTs patients with structure heart disease.
