Relationship between fractional esterification rate of high density lipoprotein cholesterol and coronary artery disease

VernacularTitle:高密度脂蛋白胆固醇酯化速率与冠心病的相关性
Author: Wen MAO ¹ ; Jun DONG ; Hong-Xia LI ; Min ZHOU ; Han-Bang GUO ; Shu WANG ; Wen-Xiang CHEN ; Qing HE
Author Information

1. 煤炭总医院
Keywords: Coronary disease; Cholesterol,HDL; Esteriftcation
From: Chinese Journal of Cardiology 2011;39(5):402-405
CountryChina
Language:Chinese
Abstract: Objective To assess the relationship between fractional esterification rate of high density lipoprotein cholesterol(FERHDL)and coronary artery disease.Methods A total of 131 hospitalized patients underwent coronary angiography due to chest pain were included in the study and Datients were divided into CAD group(n=76)and non CAD group(n=55)according to coronary allgiograrn.Clinical and laboratory data including biochemical laboratory,FERHDL and lipid subclasses were analyzed.Results The FERHDL value of CAD group was significantly higher than that of the non CAD group(21.70±8.73 vs.18.65 4±6.26,P<0.05).There was an increased trend of FERHDL with numbers of diseased coronary arteries,significant difference was evidenced between non CAD group and 3-vessel group(18.65±6.26 vs.24.00±9.22,P<0.05).FERHDL was positively correlated with TG(r=0.647,P<0.001).LDLb-C(r=0.441,P<0.001)and negatively correlated with HDL-C(r=-0.708,P<0.001)and HDL2-C(r=-0.748,P<0.001).Conclusion Our data showed that the values of FERHDL were significantly increased in CAD patients and correlated with the severity of the CAD.