A Case of Primary Gastric Choriocarcinoma Presenting with Amenorrhea.
- Author:
Seung Hyun NAM
1
;
Seock Ah IM
;
Ki Sun BAE
;
In Sook KANG
;
Jung Mi KWON
;
Kyung Eun LEE
;
Hye Sung MOON
;
Sun Hee SUNG
;
Woon Sup HAN
;
Chu Myong SEONG
;
Soon Nam LEE
Author Information
1. Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea. moisa @ewha.ac.krs
- Publication Type:Case Report
- Keywords:
Choriocarcinoma;
Stomach;
Human chorionic gonadotrophin;
Chemotherapy
- MeSH:
Adult;
Amenorrhea*;
Anaplasia;
Biopsy;
Choriocarcinoma*;
Chorion;
Diagnosis;
Drug Therapy;
Female;
Gestational Trophoblastic Disease;
Humans;
Metrorrhagia;
Nausea;
Necrosis;
Pregnancy;
Prognosis;
Stomach
- From:Cancer Research and Treatment
2002;34(6):457-460
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary gastric choriocarcinomas are very rare, and their prognosis is extremely poor. A 37-year-old woman presented with amenorrhea, vaginal spotting and severe nausea, which mimicked a pregnancy and gestational trophoblastic disease. The serum level of the beta-subunit of human chorionic gonadotrophin (beta-hCG) was significantly increased. An endoscopic biopsy of the stomach mass showed the features of a choriocarcinoma, with marked anaplasia and necrosis. Immunohistochemical staining for beta-hCG showed positive results in the choriocarcinoma. Chemotherapy for the choriocarcinoma was administered, but she died 8 months following diagnosis.
