Association of carotid atherosclerosis and blood pressure variation
10.3760/cma.j.issn.0253-3758.2011.06.002
- VernacularTitle:高血压病患者颈动脉粥样硬化与血压变异的相关性
- Author:
Ao-Ya LIU
1
;
Zhen-Qiu YU
;
Wen-Hua WANG
;
Xiao-Hui YANG
;
Qiang YONG
Author Information
1. 首都医科大学附属北京安贞医院
- Keywords:
Hypertension;
Carotid artery plaque;
Variation of blood pressure
- From:
Chinese Journal of Cardiology
2011;39(6):484-487
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship of carotid artery plaque and blood pressure variation and cardiovascular risk factors.Methods We retrospectively analyzed clinical data of in-patients treated in the department of hypertension between April 2009 and June 2010.Information on carotid ultrasonography and other clinical date were obtained from 408 patients.All patients were monitored by ambulatory blood pressure.Results (1) Carotid artery determined in plaque was 55.3%,there was no differences between men and women.However,the carotid artery plague was associated positively with age.Increased age was associated with a significantly increased positive rate.(2) Cardiovascular risk factors and carotid artery plaque: carotid artery plaque was associated with duration of disease, fasting blood sugar, total cholesterol, and low density lipoprotein-cholesterol.(3) 24 h ambulatory blood pressure and carotid artery plaque: the prevalence of carotid artery plaque increased with increasing coefficient of systolic variation (P=0.001).There was no correlation between the coefficient of diastolic variation and the prevalence (P=0.644).(4) Multivariate regression analysis indicated that carotid artery plaque was associated with duration of hypertension, 24 h mean systolic blood pressure, and coefficient of variation of 24 h blood pressure (P<0.05 ).Conclusion Carotid atherosclerosis is independently associated with coefficient of variation of blood pressure, especially with coefficient of variation of systolic blood pressure.
