Myocardial perfusion evaluation post percutaneous transluminal septal myocardial ablation in patients with hypertrophic obstructive cardiomyopathy by 99Tcm MIBI SPECT MPI
10.3760/cma.j.issn.0253-3758.2011.06.005
- VernacularTitle:核素心肌灌注显像评价经皮室间隔化学消融术治疗肥厚型梗阻性心肌病疗效
- Author:
Xiao-Xin SUN
1
;
Yue-Qin TIAN
;
Shu-Bin QIAO
;
Jian-Song YUAN
;
Fu-Jian DUAN
;
Dao-Yu WANG
;
Feng GUO
;
Zuo-Xiang HE
Author Information
1. 中国医学科学院,北京协和医学院,阜外心血管病医院
- Keywords:
Cardiomyopathy,hypertrophic;
Tomography,emission-computed,single-photon;
Catheter ablation
- From:
Chinese Journal of Cardiology
2011;39(6):497-502
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the myocardial perfusion and function in patients with hypertrophic obstructive cardiomyopathy (HOCM) before and after percutaneous transluminal septal myocardial ablation (PTSMA).Methods Sixty-eight patients with hypertrophic obstructive cardiomyopathy were included and 99 Tc m -MIBI SPECT MPI was applied before and at 1 week after PTSMA, six-month follow-up was finished in 11 patients. Semi quantity and QGS quantity perfusion and function assessment was performed in 17 LV segments.Results Myocardial perfusion post-PTSMA was significantly reduced in 98% patients, especially in basal anterosepta, basal inferoseptal, mid-anteroseptal, mid-inferoseptal and apical septal segments compared with pre-PTSMA (all P<0.05). Perfusion was significantly increased at 6 months follow-up than at 1 week post-PTSMA but still lower than pre-PTSMA (all P<0.05). LVEF (evaluated by gated SPECT) was similar before and after the procedure (P>0.05). Regional wall motion after PTSMA was lower than pre-PTSMA in basal anterior, basal anteroseptal, basal inferoseptal and basal inferior (P<0.05). Regional wall thinkening was lower than pre-PTSMA in basal inferoseptal, mid-anteroseptal, mid-inferoseptal (P<0.05) .Conclusions 99Tcm MIBI SPECT can be used to monitor myocardial perfusion post PTSMA in patients with HOCM.
