A Case of Cutaneous Matestasis Originating from Thymic Carcinoma.
10.5021/ad.2002.14.4.230
- Author:
Suk Jin CHOI
;
Nark Kyoung RHO
;
Jun Mo YANG
;
Eil Soo LEE
- Publication Type:Case Report
- Keywords:
Cutaneous metastasis;
Thymic carcinoma
- MeSH:
Abdominal Cavity;
Adult;
Biopsy;
Dermis;
Female;
Humans;
Neoplasm Metastasis;
Pleura;
Skin;
Thorax;
Thymectomy;
Thymoma*;
Tomography, X-Ray Computed
- From:Annals of Dermatology
2002;14(4):230-234
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a case of cutaneous metastasis of thymic carcinoma in Korean. A 44-year-old female, who had been diagnosed as thymic carcinoma and treated with total thymectomy and post-operative radiation therapy, presented grouped erythematous papules on the left chest. CT scans revealed metastatic lesions in the left pleura and abdominal cavity. Histopathologic examination of skin biopsy showed extensive infiltration of malignant cells in dermis and subcutis. The morphology of infiltrating cells was similar to that of tumor cells from primary thymic carcinoma specimen. The results of immunohistochemical study for skin biopsy were consistent with the features of non-neuroendocrine thymic carcinoma. Histopathologic and immunohistopathologic similarity between cutaneous lesion and previous tumor suggested that malignant cells in the skin lesion could originate from progressing thymic carcinoma.
