A novel approach to quality evaluation of root of Scutellaria baicalensis by DPPH free radical scavenging.
- Author:
Yu-ping LIU
1
;
Purusotam BASNET
;
Katsuko KOMATSU
;
Hui CAO
Author Information
- Publication Type:Journal Article
- MeSH: Biphenyl Compounds; Flavanones; Flavonoids; chemistry; isolation & purification; pharmacology; Free Radical Scavengers; pharmacology; Free Radicals; Molecular Structure; Picrates; Plant Roots; chemistry; Plants, Medicinal; chemistry; Quality Control; Scutellaria baicalensis; chemistry
- From: China Journal of Chinese Materia Medica 2002;27(8):575-619
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo develop a simple, reliable approach for evaluating the quality of Huangqin (Scutellaria baicalensis).
METHODTo determine the DPPH free radical scavenging activity and assay of four bioactive components: baicalin, baicalein, wogonin and wogonin-7-O-glucuronide by HPLC.
RESULTThe correlative relationship between DPPH free radical scavenging activity and baicalin content was obtained.
CONCLUSIONBioassay of DPPH free radical scavenging activity could be used as one of the methods for quality evaluation of Chinese drug Huangqin.
