Experimental study on Rhizoma sparganii and Radices zedoariae treating hepatic fibrosis.
- Author:
Zhu-ting XI
1
;
Chang-min SHAN
;
Xue-lian JIANG
;
Xi-ying LUAN
;
Ke-ke LI
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Curcuma; chemistry; Drugs, Chinese Herbal; isolation & purification; therapeutic use; Liver Cirrhosis; drug therapy; pathology; Magnoliopsida; chemistry; Male; Phytotherapy; Plant Roots; chemistry; Plants, Medicinal; chemistry; Rats; Rats, Wistar; Rhizome; chemistry
- From: China Journal of Chinese Materia Medica 2002;27(12):929-932
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effects of rhizoma sparganii and radices zedoariae on hepatic fibrosis.
METHODThe rat immunohepatic fibrosis model was made by intraperitoneal injection of porcine serum and treated with rhizoma sparganii and radices zedoariae. The ALT, GGT, TP, ALb, A/G, IVC, LN, HA and the pathological change of the liver were observed.
RESULTRhizoma sparganii and radices zedoariae could increase TP, ALb, A/G, decrease ALT, GGT, IVC, LN, HA and improve the pathological change.
CONCLUSIONRhizoma sparganii and radices zedoariae can protect hepatic cells, alleviate degeneration and necrosis, recover structure and function, and reduce the proliferation of fibrous tissue.