Effects of antioxidation and ceramide of improved prescription of didang-tang (IPDT) on exprimental atherosclerosis rabbits.
- Author:
He-qing HUANG
1
;
Sha TAO
;
Pei-qing LIU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Antioxidants; pharmacology; Arteriosclerosis; metabolism; Ceramides; metabolism; Cinnamomum; chemistry; Drug Combinations; Drugs, Chinese Herbal; isolation & purification; pharmacology; Female; Leeches; chemistry; Male; Materia Medica; pharmacology; Plants, Medicinal; chemistry; Rabbits; Rheum; chemistry
- From: China Journal of Chinese Materia Medica 2002;27(12):942-944
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effects of antioxidation and ceramide content of improved prescription of Didang-tang (IPDT) on exprimental atherosclerosis(AS) rabbits.
METHODPlasm Superoxide Dismutase(SOD) activity was detected with micro-content fast detecting method, Plasm Malondialdehyde(MDA) content with improved BaMuGuoFu method, and Aortic Ceramide (CER) content with thinlayer scanning.
RESULTIPDT could effectivly improve plasma SOD activity and decrease plasma MDA content and decrease aortic CER content.
CONCLUSIONIPDT on exprimental AS is related to the improvement of antioxidation and decrease of CER content.
