Kinetic study on the volatility of menthol and borneol.
- Author:
Jie-ming ZOU
1
;
Li-sheng WANG
;
Hui WEN
;
Shu-lin WANG
Author Information
- Publication Type:Journal Article
- MeSH: Bornanes; administration & dosage; chemistry; Cyclodextrins; Drug Carriers; Drug Stability; Drugs, Chinese Herbal; administration & dosage; chemistry; Menthol; administration & dosage; chemistry; Tablets; Temperature; Volatilization; beta-Cyclodextrins
- From: China Journal of Chinese Materia Medica 2002;27(10):739-742
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the volatile regularity of menthol and borneol in granule and lozenge at different temperature.
METHODKinetic method with GC being detection technique.
RESULTThe volatility of menthol and borneol acts as a pseudo first-order reaction in open system. Under the same condition, the volatile rate of menthol and borneol in granule is four times as fast as that in lozenge, and the volatile rate of borneol is faster than that of menthol.
CONCLUSIONThis study can be applied to improve the quality of lozenges containing menthol or/and borneol.
