Study on HPLC fingerprint of the triterpene acids in Poria cocos.
- Author:
Gang DING
1
;
Zhen-zhong WANG
;
Chen-feng ZHANG
;
Long-sheng SHENG
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, High Pressure Liquid; methods; Polyporales; chemistry; Triterpenes; analysis; classification
- From: China Journal of Chinese Materia Medica 2002;27(10):756-758
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo establish a method for HPLC fingerprint determination of the triterpene acids in Poria cocos.
METHODRP-HPLC, linear gradient elution and LC/MS, etc. were used to optimize the fingerprint determination method, and identify the main peaks in the HPLC fingerprint.
RESULTA preferable method for HPLC fingerprint determination of the triterpene acids in P. cocos was established, and 9 peaks in the HPLC fingerprint were identified.
CONCLUSIONA general acquaintance of the triterpene acids in P. cocos can be obtained by using the preferable HPLC fingerprint determination method, which is useful for quality evaluation of the crud drug of P. cocos.
